PKC, which stands for problem-knowledge coupling, is the brainchild of Dr. Lawrence Weed, creator of the problem-oriented medical record and the subjective, objective, analytical, and planning (SOAP) approach to clinical progress notes. Weed has never been a fan of evidence-based medicine because it still relies on probabilities. Instead, he prefers the computer-aided "coupling" of medical knowledge to a specific patient's set of problems, based on the theory that the human brain could possibly recall and apply all relevant learning to the patient's current condition at the point of care.
Weed has left the company he founded, but his philosophy remains in PKC's products, though the Burlington, Vt.-based vendor does call its recommendations evidence-based. Advisor, a CDS system for clinicians, helps with differential diagnoses and care plans. A consumer-focused version called Profiler is an interviewer, gathering medical history and other information directly from the patient and presenting questions based on each response. This program can create the subjective portion of the SOAP note for export to an EHR or personal health record.