How Penn Medicine Mines E-Records For Clinical Trial Prospects - InformationWeek
Healthcare // Analytics
04:35 PM
Ransomware: Latest Developments & How to Defend Against Them
Nov 01, 2017
Ransomware is one of the fastest growing types of malware, and new breeds that escalate quickly ar ...Read More>>

How Penn Medicine Mines E-Records For Clinical Trial Prospects

It shows a hospital wringing value out of an electronic record system that took years to implement. One in a series of profiles of InformationWeek 500 innovators.

When recruiting patients for clinical trials, medical researchers still typically get word out with billboards and newspaper ads. Some have tried Facebook lately. But those methods generally don't attract enough of the right patients, delaying research and sometimes leading to trial cancellations.

Penn Medicine, part of the University of Pennsylvania Health System, is trying something new: using the trove of data in electronic medical records to find clinical trial candidates and then alert those patients' doctors.

It's an example of how healthcare IT teams are working to wring value from the electronic record systems they've often spent years implementing. Earlier this year Penn Medicine completed a five-year project to roll out Epic e-records to its 1,800 employed physicians. "You often need an army to install EMR systems," says Michael Restuccia, CIO of the University of Pennsylvania Health System. "But once you finally have these systems in place, the amount of effort to get added value out of them with programs like this is comparatively little."

The provider's new clinical trial application, called Penn Research Trial Advisory, took several months to develop. It has piloted the app in its ob-gyn department, helping recruit 200 patients for infertility clinical trials. The test brought an 87% increase in the number of physician-referred patients for trials compared with the prior four-month period.

"The key is the much more targeted, available information sitting in the EMR that's now turned into a tremendous asset," says Brian Wells, Penn Medicine's associate CIO. Other departments plan to use the app for their own clinical trials.

In general, 85% to 95% of patient care is provided by ambulatory care clinicians--doctors in their offices or other locations outside in-patient hospital settings. Because they tend to have a more ongoing, trusting relationship with their patients, those docs are best positioned to recruit patients for clinical trials, Restuccia says. It's more likely than an ad to produce the right conditions, as well.

How It Works

Penn Medicine is looking to do more with its electronic health records
Penn Medicine is looking to do more with its electronic health records

Once researchers identify the candidate criteria for a clinical research trial--diagnosis, sex, age, lab results, and medication--the criteria are embedded as an alert in the ambulatory EMR. In the infertility clinical trials, criteria include data such as codes for a diagnosis of polycystic ovaries.

If a patient matches the criteria, his or her doctor gets a message on the patient's EMR screen. Wells calls it a "gentle reminder" for the physician to mention the trial to an appropriate candidate. Physicians can also select a link to learn more about the trial before discussing it with their patients, and they can print out material for patients.

If the patient's interested, the physician can send an email from the EMR to someone trained to discuss the research. If the patient decides to participate, it's noted in the electronic chart so other physicians won't ask the patient to take part in other trials.

The app's development team included several clinicians and researchers and a small IT team--mostly just one Epic EMR team member, who programmed the rules. "The hardest part of the project was getting clinicians to agree on the rules so that you don't generate a lot of false positives," Wells says.

The clinical trial advisory app showed Penn Medicine's team how it can leverage the huge investment in EMRs. More important, Restuccia says, it's moving Penn Medicine toward its bigger goal of providing "more personalized medicine."

Go to the 2011 InformationWeek 500 homepage

Comment  | 
Print  | 
More Insights
Newest First  |  Oldest First  |  Threaded View
How Enterprises Are Attacking the IT Security Enterprise
How Enterprises Are Attacking the IT Security Enterprise
To learn more about what organizations are doing to tackle attacks and threats we surveyed a group of 300 IT and infosec professionals to find out what their biggest IT security challenges are and what they're doing to defend against today's threats. Download the report to see what they're saying.
Register for InformationWeek Newsletters
White Papers
Current Issue
2017 State of IT Report
In today's technology-driven world, "innovation" has become a basic expectation. IT leaders are tasked with making technical magic, improving customer experience, and boosting the bottom line -- yet often without any increase to the IT budget. How are organizations striking the balance between new initiatives and cost control? Download our report to learn about the biggest challenges and how savvy IT executives are overcoming them.
Twitter Feed
Sponsored Live Streaming Video
Everything You've Been Told About Mobility Is Wrong
Attend this video symposium with Sean Wisdom, Global Director of Mobility Solutions, and learn about how you can harness powerful new products to mobilize your business potential.
Flash Poll